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TRANSLATIONAL RESEARCH CORE FACILITY

• View Available Tissue

• Tissue Request Form

• Histology Immunohistochemistry Form

• Laser Capture Microdissection Request Form

This Facility provides the KCC with five core functions:

1. Tissue procurement, banking, and distribution
   
2. Tissue processing and Histology services; frozen and fixed tissues
   
3. Microdissection of tissues and laser capture of individual cells
   
4. Immunohistochemical staining of tissue sections
   
5. Quality assurance and clinical-pathologic data collection.
   

Note: (all protocols must have IRB approval before requesting tissues)

Frozen and paraffin embedded tissues are available to participating scientists either from the tissue bank, or from paraffin block archives. Basic histologic services include processing, slide preparation and staining of human and animal tissues. Immunohistochemical staining is performed on paraffin sections, frozen tissue or cytologic preparations, utilizing a broad range of commercial antibodies or reagents provided by the investigator. Specimens requiring microdissection or laser capture of individual cell types are processed via microscopic evaluation by the Core surgical pathologists. All specimens are reviewed as to organ type, tumor content, and tissue viability. Where appropriate and IRB approved, clinical-pathologic data can be requested.

Links to request forms for most Facility services are provided above and can be downloaded and filled out. Requests for archived blocks should go to 285 Main; tissue requests should be discussed with Dr. McCue (5-5588), or a collaborating pathologist so that the archive search can be scheduled.

Immunohistochemistry requests for standard antisera should go to Rm. 529 JAH, as should all histology requests (processing of tissues, embedding, sections, H&E, other stains). Histology and Immunohistochemistry request forms with relevant tissues or blocks should be delivered to Rm. 529 JAH, X3-3858.

Microdissection requests and requests for Pathology review of sections and slides should be made to individual collaborating surgical pathologists. Laser Microdissection requests should be discussed with Mark Curtis.

Questions about Facility use and services? Contact Raffaele Baffa (5-6961), Magdalena Potoczek (3-3858) or Peter McCue (5-5588).

TRANSLATIONAL RESEARCH CORE FACILITY PERSONNEL

Histology/Immunohistochemistry